Trans20: A Longitudinal Cohort Study to Improve Outcomes for Transgender Children and Adolescents

Feasibility of a codesigned group cognitive behavioral therapy intervention for trans young people targeting gender minority stress.

Alessandra Chinsen, Michelle A Tollit, Ken C Pang, Jess Wilson, Eliza Burnie, Sam Hay, Eve Millington, Kayden Crombie, Zeffie Poulakis, Chris Pepping, Carmen C Pace, Timothy J Cronin

2026-04-16

Trans and gender diverse (hereafter trans) youth are likely to experience poor mental health and report elevated rates of depressi..

Is there an association between pelvic pain and gender-affirming testosterone therapy in trans masculine adolescents? An exploratory cross-sectional study

D Moussaoui, M Hoq, CV Elder, SR Grover, MA O'Connell, KC Pang

2026-01-01

Background: High rates of pelvic pain have been reported in trans individuals on testosterone, but the pathophysiology of pain and..

Operationalising social transition in trans and gender diverse youth: a scoping review of definitions and measures

W Conabere, F Lami, H Andrews, M Skarlatos, CC Pace, P Buckingham, S Hay, T De Ieso, KC Pang, MA Tollit

2026-01-01

Background: Social transition can be an important and accessible aspect of gender affirmation, allowing trans and gender diverse y..

Genetic and Environmental Contributions To Gender Diversity: A Systematic Review of the Twin Literature

W Conabere, L Bourchier, S Malta, A Ravine, KC Pang

2025-09-01

Amidst growing visibility of gender diversity, the aetiology of gender identity has become a subject of increasing public interest..

Frequency, Timing, and Management of Erythrocytosis in Adolescents Receiving Gender-Affirming Testosterone Therapy—A Retrospective Study

A McLean, M Hoq, KC Pang, M O’Connell

2025-08-01

Erythrocytosis is a well-described effect of testosterone therapy in adults, but less is known about this phenomenon in transgende..

Individualized and innovative gender healthcare for transgender and nonbinary youth

DBA Clark, DL Metzger, KC Pang, C St. Amand, K Khatchadourian

2025-07-01

Increasing numbers of transgender and nonbinary youth are now accessing gender-affirming medical interventions, which have been de..

Capturing Gender Diversity in Twin Research

W Conabere, A Ravine, L Bourchier, S Malta, J Tyler, S Li, JL Hopper, KC Pang

2025-04-01

Most twin registries have not systematically collected the data required to determine gender identity, which has limited opportuni..

Effect of assigned sex on the age at which individuals seek specialist gender affirming care

FK Kahn, CM Wiepjes, D Colon-Cabrera, MA Tollit, M Hoq, D Feldman, A Ravine, R Lane, TD Steensma, KC Pang

2025-01-01

Background: Citing fears of possible social contagion, opponents of medical care for transgender youth have raised concerns over r..

Epigenetic remodeling by sex hormone receptors and implications for gender affirming hormone therapy

D Celestra, NNL Nguyen, C Laberthonniere, KC Pang, R Saffery, RA Davey, M Mhlanga, AS Cheung, B Novakovic

2025-01-01

Sex differences in immune system development and response to pathogens has been well documented, with females exhibiting more favo..

Evaluating the benefits and risks of puberty blockers and gender-affirming hormones for transgender adolescents

D Wright, KC Pang, S Giordano, L Gillam

2025-01-01

The use of puberty blockers and gender-affirming hormones by transgender adolescents is the subject of an ongoing public debate. I..

“I could be one of those people that’s alive and happy”: a qualitative exploration of a co-designed group therapy program targeting gender minority stress for trans young people (TAG TEAM)

A Chinsen, MA Tollit, PL Heye, KC Pang, TJ Cronin, CC Pace

2025-01-01

Background: TAG TEAM is a novel group cognitive behavioral therapy (CBT) program for trans young people which targets gender minor..

Social transition in young trans people accessing gender-affirming care

P Buckingham, MA Tollit, G Wong, R Wijesuriya, M Hoq, CC Pace, KC Pang

2025-01-01

Background: In-depth quantitative study of how young people undertake social transition is lacking. We aimed to provide a comprehe..

Safeguarding the health and wellbeing of transgender young people

C Pace, A Chinsen, AS Cheung, SR Skinner, KW Knight, MA Tollit, MM Telfer, KC Pang

2024-11-18

Transgender (hereafter referred to as trans) people have a gender that is different from the sex assigned to them at birth (Box 1)..

A comparison of gender diversity in transgender young people with and without autistic traits from the Trans 20 cohort study

Michelle A Tollit, Tiba Maloof, Monsurul Hoq, Kristina Haebich, Carmen C Pace, Zamantha Munoz Rodriguez, Muhammad Sial, Jonathan M Payne, Ken Pang

2024-06-01

BACKGROUND: There is an elevated co-occurrence of autism in trans individuals, with recent meta-analyses suggesting that 11% of tr..

Prevalence of Eating Disorder Symptoms in Transgender and Gender Diverse Adolescents Presenting for Gender-Affirming Care

JA Kerr, J Paine, E Thrower, M Hoq, C Mollica, SM Sawyer, PS Azzopardi, KC Pang

2024-04-01

Purpose: To describe the prevalence of eating disorder symptoms among adolescents seeking gender-affirming care. Methods: Cross-se..

Characteristics of Menstrual Suppression and Its Association With Mental Health in Transgender Adolescents

D Moussaoui, MA O'Connell, CV Elder, SR Grover, KC Pang

2023-11-01

OBJECTIVE:To investigate the prevalence, nature, and effectiveness of menstrual suppression in transgender and gender-diverse (TGD..

Assessment of Quality of Life of Transgender and Gender-Diverse Children and Adolescents in Melbourne, Australia, 2017-2020

L Engel, I Majmudar, C Mihalopoulos, MA Tollit, KC Pang

2023-02-02

Importance: Transgender and gender-diverse (TGD) children and adolescents may experience not only gender dysphoria but also depres..

Gender identity questionnaire for children: An alternative scoring approach reflecting a child’s affirmed gender identity

M Hoq, F Lami, MA Tollit, KC Pang

2023-01-01

Cardiometabolic Outcomes in Transgender Youth

MA O'connell, KC Pang

2022-12-01